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The rate-limiting substrate for glutathione production appears to be cysteine, hence why N-acteylcysteine has such a multitude of health benefits in clinical practice and research

Doctors used this medicine to treat: Chronic liver diseases Alzheimers disease Patients who were undergoing chemotherapy It had a long history as a medication for these conditions before anyone focused on its cosmetic benefits The Accidental Discovery The key discovery of Glutathiones effect on skin color came about completely by chance Patients who were taking Glutathione for months, and sometimes years, to treat their serious illnesses (like those listed above) began to notice something unexpected As a side effect of this long-term treatment, their skin color gradually became lighter When this significant side effectthe lightening of skin colorwas observed, it sparked extensive studies and research into exactly how Glutathione affects skin pigment