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Immune signaling also touches skin repair, since inflammation can slow collagen repair and can push hairs into a rest phase after illness or infection

As the importance of R-2-HG in boosting tumor initiation, proliferation and metastasis is emphasized, identifying whether metabolic enzymes or transporters associated with glutamine metabolism could be involved in the generation of R-2-HG is interesting

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Its expression is evident in renal impairment and inflammatory reactions (Ansari et al

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