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Several metabolic adaptations make it challenging to sustain weight loss long-term, including hormonal changes, increased food noise, and the energy gap. Shifts in Hunger Hormones Hunger and satiety are partially driven by hormones released from the gut to the hypothalamus (a region of the forebrain)

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To take advantage of this rather popular side effect, the pharmaceutical giant launched another product called Wegovy to target weight loss in 2021

Many patients also benefit from eating smaller, more frequent meals rather than three large ones, which reduces the volume of food your slowed stomach must process at once

It can eventually lead to anemia, in which your body doesnt have enough healthy red blood cells to carry oxygen to tissues