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We recently demonstrated that G6PD deficiency could be induced by either pharmacological inhibitors or G6PD siRNA, which impairs redox homeostasis and causes increased ROS levels and reduced GSH levels in monocytes and endothelial cells

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It has been shown that melatonin is capable of indirectly scavenging free radicals by regulating the activity and expression of other antioxidant systems in both plant and mammals (Bidabadi et al

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