Rodbard HW, Rosenstock J, Canani LH, Deerochanawong C, Gumprecht J, Lindberg SO, et al
It doesnt necessarily kill all microorganisms on contact (that would be bactericidal), but it effectively inhibits their growth and reproduction
J Infect Dis 158(2):474477 Curtis BR, McFarland JG, Wu GG, Visentin GP, Aster RH (1994) Antibodies in sulfonamide-induced immune thrombocytopenia recognize calcium-dependent epitopes on the glycoprotein IIb/IIIa complex
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Moreover, these analyses have already been done in conventional meta-analyses, showing for SGLT-2 inhibitors the lack of significant difference in the reduced risk of the composite outcome (CV death + HHF) in patients with or without type 2 diabetes or in subjects of 65 years of age or younger vs those older than 65 years of age [13]
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