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These side effects may include: vomiting nausea diarrhea constipation bloating gas and belching heartburn stomach flu dehydration, especially in people with kidney failure More serious side effects may include: pancreatitis (inflammation of the pancreas) severe stomach problems GLP-1 agonists are approved for people with type 2 diabetes to manage their blood sugar levels, and some are approved for weight loss

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Retatrutide is a synthetic peptide that acts as a GLP-1 receptor agonist , involved in regulating glucose metabolism , insulin secretion , and appetite signaling

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