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PMID: 10470368 DOI: 10.1016/s0065-2571(98)00029-6

406 FGF21 is recognized as a stress response factor that addresses mitochondrial dysfunction in cells

Mechanisms of IGF-1-mediated regulation of skeletal muscle hypertrophy and atrophy

PFOS reduced the phosphorylated levels of mTOR and AKT and induced autophagy activation

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Based on initial results from metabolic studies and RNA-seq, and with inhibitor studies, larger effect sizes were anticipated, and a minimum of n 3 per group was used