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The bile acid-sequestering resin sevelamer eliminates the acute GLP-1 stimulatory effect of endogenously released bile acids in patients with type 2 diabetes

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Regarding extraction methods, eight studies employed water extraction followed by alcohol precipitation (15, 1723), while only one study did not specify the extraction process as it utilized commercially available polysaccharides (16)

Lundbeck, Janssen-Cilag, Merck, Pfizer, Sanofi Synthelabo, Servier, Solvay and Wyeth and has served as a consultant to AstraZeneca, Bioadvantex Pharma, Bristol-Myers Squibb, Eli Lilly, GlaxoSmithKline, H