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The receptor systems are completely different, and tolerance to one does not predict tolerance to the other
The freeze-thaw cycle can cause protein aggregation and denaturation, reducing potency
Let the water trickle down the inside wall of the vial
Conclusions Validation parameters including linearity, precision, and accuracy are within the ranges indicated by the FDA 33
However, their effect may be particularly dose-dependent and more research is needed before specific recommendations can be made
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