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10.1186/1471-2202-13-33 62 IsacsonR.NielsenE.DannaeusK.BertilssonG.PatroneC.ZachrissonO.et al
SIDE AFFECT : SKIN WHITENING
Plaintiffs allege manufacturers Novo Nordisk and Eli Lilly failed to adequately warn prescribers and patients about the risk of NAION and sudden vision loss associated with GLP-1 drugs
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That number is not just large in absolute terms, it is the largest weight-loss signal ever reported in a randomized Phase 3 trial of a GLP-1-class compound, and it arrived with additional secondary findings that reframe what "GLP-1 therapy" could eventually mean: a 75.8% reduction in osteoarthritis pain, a roughly 20% drop in LDL cholesterol, and a 72% reversal rate of prediabetes to normoglycemia in the affected subpopulation
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