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For background on the broader angiotensin IV / AT4 system the work was built on, see Wright and Harding 1995 (PMID 7768321) and Wright et al

Some practitioners recommend continuous low-dose maintenance therapy for ongoing anti-aging effects, particularly in individuals over 40 years old

10.1007/s11357-011-9212-x Age 19 Brown-BorgH

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Another example would be popular hair dyes which rely on corrosive chemical processes, resulting in acute or chronic side effects, including dry, split, and dull hair shafts [20], anaphylaxis [76], alopecia [92], urticarial [47], and cancer [112, 270, 276, 277], and they do not address the root cause of hair greying