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J Neurosci 30(15):54375450 Ferrini F, De Koninck Y (2013) Microglia control neuronal network excitability via BDNF signalling

For many higher risk patients, the future monitoring model probably needs to combine body composition with functional and clinical context, not interpret lean mass changes in isolation

However, it is not yet FDA-approved or available by prescription

According to the Summary of Product Characteristics (SmPCs) for Wegovy and Saxenda, gallstones are not listed as a contraindication, though gallbladder events are noted as a known risk

To manage digestive conditions and side effects while taking a GLP-1 agonist, follow these tips: follow the dosage instructions exactly as prescribed slowly increase your fiber intake, as recommended by your healthcare professional consider taking fiber supplements if constipation occurs drink plenty of water to remain hydrated eat small, frequent meals rather than large meals avoid eating too close to bedtime avoid spicy or fatty foods exercise regularly to aid with digestion GLP-1 medications are highly effective for weight management and type 2 diabetes management

Want to understand if GLP-1 therapy fits your health plan