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Together, these strategies aim to establish a closed-loop framework linking mechanistic insight, targeted delivery tools, and clinical validation, accelerating the translation of ferroptosis-based interventions toward precision treatment in AD

[14] [15] Semaglutide may be used as monotherapy or in combination with other antidiabetic medications, including metformin, sulfonylureas, sodium-glucose cotransporter-2 (SGLT2) inhibitors, and insulin

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Keywords: type 2 diabetes, incretins, glucagon-like peptide-1, glucose-dependent insulinotropic polypeptide Introduction: The Incretin Effect in Health and Disease The gastrointestinal system has an intricate pathway of hormones that are released from the gut lining upon ingestion of food and regulate glucose metabolism and appetite