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[1] Dosing is individualized to body weight, severity of deficiency, and clinical context

For those of us with complex, multi-system conditions like MCAS or heritable connective tissue disorders, it may translate into improvements across multiple areas of dysfunction

What warrants investigation: Complete cessation of menstruation (amenorrhea) beyond 3 months, heavy breakthrough bleeding, or symptoms of hypothyroidism co-occurring with cycle changes should be evaluated by a provider

But most men find their alcohol tolerance drops significantly, and alcohol can worsen GI side effects