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In sum, current evidence positions GLP-1 RAs as a potential cardioprotective strategy in HF, with HF with preserved ejection fraction emerging as the clinically most relevant phenotype for the drug class, especially when occurring in people with obesity with and without diabetes

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Furthermore, programmed necrosis can also be influenced by ROS, which promote the formation of a stable association between two serine/threonine kinases, namely RIP1 and RIP3, which mediate the complex formation of programmed necrosis (Figure 1) (22, 24, 46, 47)

It is well known that lipid mobilization is the main metabolic adaptation to starvation

Doctors give it to people who have diabetes to see if their blood sugar levels are under control