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Hydrocortisone and dexamethasone prevent TNF--triggered sloughing of the glycocalyx, thereby improving vascular endothelial function [21, 119, 120]

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Cathepsin G inhibition by Serpinb1 and Serpinb6 prevents programmed necrosis in neutrophils and monocytes and reduces GSDMD-driven inflammation

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The reduction of hydrogen peroxide results in the formation of oxidised glutathione which then needs to be recycled back to the reduced form, as described above