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Tirzepatide is a dual GIP/GLP-1 receptor agonist, while Retatrutide (LY3437943) adds a third target the glucagon receptor making it a triple agonist studied for broader metabolic effects

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His work around enfuvirtide helped pave the way for some of the CMC approaches Lilly now relies on for its top glucagon-like peptide-1 (GLP-1) drugs