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Phase (approx.) Cagrilintide dose Frequency Weeks 14 0.25 mg Once weekly Weeks 58 0.5 mg Once weekly Weeks 912 1.0 mg Once weekly Weeks 1316 1.7 mg Once weekly Week 17 onward 2.4 mg (max studied) Once weekly This step-wise schedule mirrors the titration used in cagrilintide and CagriSema studies ( Lau et al., Lancet 2021

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Ahead, well discuss what this warning means and why theres a relationship between GLP-1s, gallstones, and gallbladder disease

Specifically, this can occur with calcium, vitamin D, iron, B vitamins (especially B1 and B12) and trace minerals including magnesium and zinc

Among these would include mild diarrhea and itching, as well as headaches and nausea

These effects are generally mild with the starting dose and tend to be self-limiting