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Both medication classes influence metabolic processes, though through different mechanisms, making it important to consider potential interactions and cumulative effects on the body's hormonal and metabolic systems

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Glucagon-like peptide-1, a new hormone of the entero-insular axis

2,6 SGLT2i represent the first class of HF drugs targeting pathophysiological mechanisms different from neurohormonal activation and providing not only cardioprotective effects but also important metabolic benefits

While the individual pathologies of MASLD and ALD are well-established, the specific pathophysiological mechanisms for MetALD development remain under active investigation and are currently considered hypothetical models that require further clinical validation

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