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The Chief Naturopathic medical officer of the Canadian College of Naturopathic Medicine wrote in 2011 serum levels of B12 not classically deficient by current laboratory standards are associated with neuropsychiatric signs and symptoms and Most clinicians do not consider vitamin B12 important unless the serum level is deficient when indicated by laboratory reference ranges

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While some peptides are still considered research compounds and not FDA-approved for general use, medical professionals can prescribe certain peptides for therapeutic purposes