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Tirzepatide, a dual GLP-1/GIP receptor agonist has been approved for glycaemic control in type 2 diabetes as well as for obesity management leading in up to 22.5% WL in phase 3 obesity trials
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(This research is predicated on a similar but smaller 2017 study, in which daily use of weighted vests slowed bone loss in older adults with obesity during a 22-week weight-loss program.) Losing weight negatively affects bones, says lead investigator Kristen M
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Increased noradrenaline reveals potential decreased oxygen delivery to active tissues
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