The large increase in metabolic demand during the first postnatal month may partly reflect that instead of purely neuronal uptake of glutamate and GABA during very early postnatal development, virtually all glutamate and some GABA now becomes accumulated twice
This leads to reduced calorie consumption and gradual, sustained weight loss
Furnsinn C, Ebner K & Waldhausl W
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Along this line, IL-6 knockout mice only display an altered metabolic phenotype when fed a high-fat diet (208)
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