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Human Clinical Trials A 12-week facial cream study enrolling 71 women with mild to advanced photoaging documented multiple improvements: increased skin density and thickness, reduced laxity, improved clarity, and reduced fine lines with decreased wrinkle depth

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Clinical studies suggest that noticeable benefits may occur within 8 to 12 weeks of consistent daily use

In practice, the timeline to generic entry depends on: last relevant composition patent expiration, whether use patents survive, whether exclusivity (regulatory) extends market protection, and whether litigation blocks or delays approval of biosimilar/4th-gen analogs (depending on jurisdiction)

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When evaluating a provider, look for clear disclosure that compounded medications are not FDA-approved, identification of the actual licensed compounding pharmacy partner, LegitScript or similar third-party certification, and no use of phrases like "same active ingredient as Wegovy" without proper qualification