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The Wnt signaling pathway is mainly mediated by the activation of -catenin and the sustained accumulation of -catenin into the nucleus initiates the transcription of target genes by binding to T-cell factor (TCF)/lymphoid enhancer-binding factor transcription factors (97)

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Unfortunately, a study published in JAMA, found that the use of certain diabetes or weight loss medications (i.e., GLP-1 agonists such as Ozempic, Mounjaro, Wegovy, or Rybelsus) may be associated with an increased risk of developing stomach paralysis or gastroparesis

In Supplementary Tables S4 and S5 are reported the statistically significant differences obtained by comparing the levels of e-GST and e-CAT enzymatic activities in different species

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