But only a maximum of 5mcg of B12 enters the bile every day (according to "Advanced Haematology" 7th edition textbook, page 60), so it seems that only an additional 5mcg would be lost daily if none was recovered
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Injectable B12 may deliver better results because: Direct bloodstream access bypasses digestive absorption barriers Higher bioavailability allows for less frequent dosing Consistent therapeutic levels maintain steady benefits [6] Disclaimer: The FDA does not approve compounded medications for safety, quality, or manufacturing