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However, overuse or use on sensitive skin can lead to irritation or barrier disruption

10.1016/s0891-5849(01)00751-1 Free Radic Biol Med

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Bushweller, J

The review confirmed that TB4 is released by platelets, macrophages, and many other cell types following injury, where it protects cells and tissues from further damage and reduces apoptosis, inflammation, and microbial growth