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Current Therapeutic Research 1989;46(6):1027-1033

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Amylin analogs like cagrilintide appear to act via hindbrain satiety circuits and may also influence reward-related pathways involving AgRP and POMC neurons

Having said that, compounded semaglutide can be a helpful option during Ozempic and Wegovy shortages , as well as for people who cannot take Ozempic and Wegovy in their standard form

Yi C, Pan X, Yan H, Guo M, Pierpaoli W

Thyroid function should be checked, especially in women with Hashimoto disease on HRT, as hypothyroidism also causes cold intolerance