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Cisplatin is a nonspecific cytotoxic drug targeting the cell cycle by inhibiting the DNA replication process in cancer cells and damaging the structure of the cell membrane, endowing it with broad spectrum of anticancer efficacy

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This is the reason that GSH varies less in the menstrual cycle than the steady states of GSH would suggest GSH: glutathione Because GSH changes very slowly when estradiol and S change, the GSH concentration at each time is a weighted average of both low and high GSH concentrations corresponding to many different S values