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Although antibiotics may theoretically reduce the overall infection rate, 391 multiple well-conducted clinical trials and meta-analyses have consistently shown that they do not effectively prevent specific complications, such as pancreatic infections, pneumonia, or urinary tract infections, nor do they reduce the need for invasive interventions or mortality

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"Efficacy of oral N-acetylcysteine in the treatment of acetaminophen overdose." N Engl J Med