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Improved Patient Accessibility India has one of the largest populations affected by obesity and rising diabetes prevalence
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Alvaro D, Mancino MG, Glaser S et al
Xie et al., 2016), which induces an adaptive immune response, via cytokines such as interleukin (IL)-1, IL-6, IL-12, interferon (IFN)-, IFN-, and tumor necrosis factor-alpha (TNF-) (Asea, 2007
A Novo Nordisk spokesperson pointed out that NAION is not listed on approved labels as an adverse drug reaction for the marketed formulations of semaglutide. They also noted limitations in the Mass Eye and Ear study, such as its small and non-randomized sample group
Second, people with greater risk for mood disorders or depression could be less likely to take GLP-1RAs in the long term, potentially leading to reverse causality
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