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Hydroxyl radicals generated via Fenton reactions directly increase cerebral edema by impairing ion homeostasis
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2.9 Flow cytometric cell sorting analysis Following the procedure described in Section 2.2, HUVEC cells were digested and collected using trypsin without EDTA
Using co-immunoprecipitation (CO-IP), the study confirmed that FOXO4-DRI prevents FOXO4 binding to p53, facilitating phosphorylated p53 nuclear exclusion, which triggers BAX upregulation and cleaved caspase-3 activation driving selective apoptosis of senescent endothelial cells
Also, it is recommended for individuals with ASD to consume a diet rich in antioxidants to protect them from oxidative stress caused by glutamate excitotoxicity [62]
Therefore, numerous studies have focused on improving the nutritional status of preterm infants, reducing the incidence of complications, and improving long-term outcomes
