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Participants will also be tested for body weight, estimated glomerular filtration rate (eGFR), urine albumin-to-creatinine ratio (UACR), and 24-hour urinary albumin excretion (UAE), both at the time of screening and at week 52 near the conclusion of the study

This can increase the risk of stimulant-related side effects such as anxiety, fast heartbeat, insomnia (trouble sleeping), feeling jittery, and others

Avoid lotions or oils

But knowing what to expect, and how to manage it, makes the experience dramatically more tolerable

Symptoms typically emerge during dose titration and often diminish over several weeks, though some individuals experience persistent gastrointestinal upset requiring dose adjustment or discontinuation

MT-II induces penile erection via brain and spinal mechanisms