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2011;3(78):78ra32
A notable example is the CUR-PPR interaction: while PPR enhances CURs bioavailability by inhibiting CYP3A4 and P-gpcritical enzymes for CUR metabolismvia competitive binding to their active sites, this inhibition prolongs systemic CUR exposure
Data are presented as mean SEM
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Rarer side effects include muscle weakness in uremic patients and seizures in those with seizure disorders
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