A peptide is not automatically safer simply because it is not a steroid
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Three are new chemical entities developed specifically for endometriosis and uterine fibroids: relugolix alone, relugolix combined (with estradiol, and norethindrone acetate), and SHR7280, a GnRH antagonist also investigated for female infertility, heavy menstrual bleeding, and prostate cancer
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It may therefore interfere with methylation- dependent metabolism and indicate poor flow through the methionine cycle