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While the exact reason is unclear, it is hypothesized that Wegovys tendency to cause gastrointestinal side effects such as nausea, vomiting, and diarrhea
doi: 10.1016/S1473-3099(23)00299-2 13 BramanteC
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One difference between their model and the one reported here is that deletion of Gclc is induced in hepatocytes of adult mice (which are slowly proliferating), compared to theirs, where deletion of Gclc occurred in hepatocytes of growing animals (which are rapidly proliferating)
Gut side effects may be more common with the blend compared to personal peptides, given that all four peptides affect gut function
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