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[17] Patients should also seek advice if they notice unexplained weight loss (beyond that expected from GLP-1 therapy), especially if you are 40 or over and have abdominal pain

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The problem with native GLP-1 is that it has a half-life of roughly 2 minutes the enzyme dipeptidyl peptidase-4 (DPP-4) degrades it almost instantly

Can microdosing GLP-1s help with reducing side effects

Bottom line: While not a treatment for ADHD itself, melatonin is a valuable nutraceutical for managing sleep problems in ADHD