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In the Diabetes Prevention Program Outcomes Study (DPPOS, N=1,800), metformin use for a mean of 12.7 years was associated with a 13% prevalence of B12 deficiency versus 5.4% in the placebo group (P 9%) impairs wound healing regardless of peptide use [4]
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Studies in Annals of the New York Academy of Sciences have referenced Epithalon within broader research into bioregulator peptides and longevity science Note: All cited research refers to laboratory and animal model studies
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Intracellular metabolites (GSH, glucose, glucose-6P, pyruvate, succinate) were measured by liquid chromatography (Vanquish HPLC Thermo Scientific) coupled to high resolution mass spectrometry (QExactive HF Thermo Scientific)
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