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Mechanism of Action Copper-binding tripeptide that activates tissue remodeling genes, promotes collagen and glycosaminoglycan synthesis, stimulates angiogenesis, and modulates metalloproteinase activity to coordinate wound healing and anti-inflammatory responses
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Bomfim TR, Forny-Germano L, Sathler LB, Brito-Moreira J, Houzel J-C, Decker H, Silverman MA, Kazi H, Melo HM, McClean PL, Holscher C, Arnold SE, Talbot K, Klein WL, Munoz DP, Ferreira ST, De Felice FG
Provides Intracellular Antioxidant Support
The potency of PF-06882961 (CS EC 50 = 13 nM) on the cAMP pathway was approximately 120- and 14-fold (Fig 3A, Table S2) lower than exenatide (CS EC 50 = 0.11 nM) and liraglutide (CS EC 50 = 0.95 nM), respectively
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