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Notably, melatonin increases p53 expression through the PI3K/Akt/mTOR signaling pathway, which plays a significant role in tumor suppression

One significant study is the altered glutamate levels in particular brain areas, including the anterior cingulate cortex

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3.5 Pharmacokinetics of GEB extract in normal and MCAO rats Pharmacokinetic profiling of six GEB-derived compounds (PA, PB, PC, PE, GAS, 4-HBG) was conducted via non-compartmental analysis following oral administration (Figure 7

This is the phase where the synergistic effects become most apparent

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