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Researchers obtained data from adults aged 40 years and older with type 2 diabetes and atherosclerotic CVD in the Optum database who were enrolled in a health insurance plan for at least 180 days prior to starting one of the three study drugs

Recent guidance emphasizes that compounded versions should only be used when medically necessary and when FDA-approved alternatives are unavailable

[6] Degradation [edit source] Once secreted, GLP-1 is extremely susceptible to the catalytic activity of the proteolytic enzyme dipeptidyl peptidase-4 (DPP-4)

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Now, some GLP1s are approved specifically for weight loss in people without diabetes

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