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In a phase II trial, participants with obesity were randomly assigned to various doses of retatrutide from 14 , 8, or 12 mg or a placebo for 48 weeks [19]

Alanine, arginine, cysteine, and proline, but not glutamine, are substrates for, and acute mediators of, the liver--cell axis in female mice

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Availability of Data and Material Not applicable Ethics Approval Not applicable Consent to Participate Not applicable Consent for Publication Not applicable Author Contributions All authors (F.P, S.M.O, J.M, F.C.S) meet ICMJE authorship criteria, made substantial contributions to the conception and design of the work and to drafting or critically revising the manuscript, approved the final version, and agree to be accountable for all aspects of the work

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