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These effects produce greater reductions in HbA1c and body weight compared with SGLT2is [19, 20]
A: Absolutely
For example, higher levels of circulating IGF are associated with increased risk of breast and prostate cancer [2, 3]
When taken as recommended, glutathione supplements are generally safe
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LEADER [29] and SUSTAIN-6 [30] reported a prespecified renal composite of new onset or persistent macroalbuminuria, persistent doubling of serum creatinine and eGFR 45 mL/min/1.73 m 2 , need for renal replacement therapy (RRT), and renal death
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