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IGF-binding proteins are multifunctional and act via IGF-dependent and -independent mechanisms

Furthermore, intravenous administration of PMO exhibits superior biocompatibility (Shan et al., 2023)

A study published in Circulation noted that while these reductions in muscle volume appear proportionate to the weight loss achieved, the concern remains that excessive lean mass loss could lead to sarcopenia, reduced metabolic rate, and poorer long-term outcomes

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Emerging role of substance and energy metabolism associated with neuroendocrine regulation in tumor cells