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To understand more about what fatty liver actually is, it helps to recognise that this condition exists on a spectrum from simple steatosis to more severe non-alcoholic steatohepatitis

A simplified reaction is shown below: 2 GSH + H 2 O 2 GSSG + 2 H 2 O Glutathione reductase (GR) changes GSSG back to GSH by using NADPH: GSSG + NADPH + H + 2 GSH + NADP + GPx and GR form the main GSH/GSSG recycling cycle