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Severe or persistent gastrointestinal symptoms may, in some individuals, lead to reduced fluid intake and a risk of dehydration

The Takeaway Wegovy and Zepbound are both FDA-approved weight loss medications that work in similar but slightly different ways, though clinical trials suggest that Zepbound may lead to greater weight loss than Wegovy

A review of current evidence for acetyl-L-carnitine in the treatment of depression

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In the SURMOUNT-1 trial, tirzepatide at the highest dose (15 mg) produced average weight loss of 22.5% versus approximately 15% for semaglutide in comparable trials

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