glp-1 regulatory news Safety Check GLP-1 RA prescription trends: January

Medication ineffectiveness

"GLP-1 receptor agonists should be prescribed alongside structured lifestyle interventionsspecifically resistance training at least 3 times weekly, 150 minutes of moderate-intensity aerobic exercise weekly, and nutrient-dense dietary counselingto preserve muscle and bone mass, optimize weight loss, and improve cardiometabolic outcomes." "Protein intake alone is insufficient without structured resistance training, and combination therapy produces superior metabolic benefits compared to pharmacotherapy alone, including better preservation of lean mass, improved cardiorespiratory fitness, and prevention of GLP-1-associated increases in resting heart rate." I wrote earlier about this balance in a piece called The central idea still holds: GLP-1 medications can improve metabolic markers dramatically, but without strength training and adequate nutrition, people may lose meaningful lean mass

Incidence of dementia and major subtypes in Europe: a collaborative study of population-based cohorts

Strandwitz P

AHK-Cu is available in topical formulations such as serums

Rare but clinically consequential eventsincluding anaphylaxis, eosinophilic pneumonia, perioperative aspiration, and ARDShave been reported in temporal association with GLP-1 RA exposure, predominantly in case reports and pharmacovigilance data of very low certainty