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Modifications can be made to the termini of existing CPPs or the peptide backbone can be adjusted, such as through peptide cyclization, to improve stability and cell permeability
The consequent release of DAMPs further activates inflammatory cascades and exacerbates surrounding tissue injury [31]
This is likely because there are two pathways for satiety, called leptin-dependent and leptin-independent pathways
While Kitano administered 1000 mg daily, we used 3000 mg, emphasizing the critical role of precise dosing for consistent fertility outcomes
doi: 10.1177/1060028017689878 64 Pharmacological profile, efficacy and safety of lixisenatide in type 2 diabetes mellitus
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