Mann JFE, rsted DD, Brown-Frandsen K, Marso SP, Poulter NR, Rasmussen S, et al
Only those who reached the maintenance dose and completed that phase were randomised to continue semaglutide or switch to placebo, with lifestyle intervention in both arms
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(B) HepG2 cells, transfected with 50 nM AMPK, SIRT6, or scrambled (Scr) small interfering RNA (siRNA) for 24 hours, were treated with 400 M PA, followed by treatment with or without 100 nM exendin-4 and liraglutide for 24 hours