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GLP-1 medications increase the time food spends in your stomach, slowing gastric emptying and signaling fullness to your brain

However, a small study that gave a group of alcoholics a low dose of semaglutide (Wegovy) over nine weeks showed an improvement in their drinking habits, including a reduction in cravings and heavy drinking days

These findings provide a plausible neurophysiological basis for the lower incidence of nausea and vomiting observed with dual GIP/GLP-1 receptor agonists, such as tirzepatide, although the detailed molecular mechanisms remain to be elucidated

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