Andrew Huberman: But normally I ask about mechanism and then I talk about protocols
They work in (slightly) different ways Zepbound and Ozempic also have distinct active ingredients that work in slightly different ways Ozempic targets GLP-1 receptors, while Zepbound targets both GLP-1 and GIP receptors
Conflict of interest Author AA has received consulting fees from AbbVie, Allergan, Amgen, Arena, Biogen, Boehringer Ingelheim, Bristol-Myers Squibb, Celgene, Celltrion, Eli-Lilly, Ferring, Galapagos, Gilead, Janssen, MSD, Mylan, Pfizer, Protagonist Therapeutics, Roche, Samsung Bioepis, Sandoz and Takeda
GHK-Cu tackles TGF-beta1 from two directions: it reduces production of the "stop growing" signal and protects the cells receiving that signal from programmed death
The Biological Explanation The article highlights that GLP-1 therapies work through several biological pathways
This creates an imbalance between reactive oxygen species and antioxidants, increasing oxidative stress and causing damage to liver and nerve cells